Publication | Open Access

Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors

Drug TargetNovel Leucyl-trna SynthetaseBiochemistryMedicineNatural SciencesRational Drug DesignMechanism Of ActionRapamycin Complex 1Drug DevelopmentChemical BiologyPharmacologySimplified Leucyladenylate SulfamatesDrug Discovery