Anti-inflammatory activity of Jatropha gossypifolia L. leaves in albino mice and Wistar rat

Abstract

Methanolic extract of Jatropha gossypifolia L. leaves showed systemic and significant anti-inflammatory activity in acute carrageenan-induced rat paw edema and chronic cotton pellet induced granuloma formation after oral treatment for 7 days in Wistar rats. Anti-inflammatory activity might be due to effects on several mediators and arachidonic granular tissue formation and leukocyte migration from vessels.