Concepedia

Publication | Open Access

Integrin-Linked Kinase Regulates Vasomotor Function by Preventing Endothelial Nitric Oxide Synthase Uncoupling

DOIFull Paper Access

64

Citations

38

References

2011

Year

Beatriz Herránz, Susana Márquez, Brenda Guijarro, Enrique Aracil, Clara Aicart-Ramos, Ignacio Rodríguez‐Crespo, Isabel Serrano, Manuel Rodrı́guez-Puyol, Carlos Zaragoza, Marta Saura
Circulation Research

Abstract

Our results identify ILK as a regulatory partner of eNOS in vivo that prevents eNOS uncoupling, and suggest ILK as a therapeutic target for prevention of endothelial dysfunction related to shear stress-induced vascular diseases.

References

YearCitations

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