KIO₃‐Catalyzed Domino C(sp²)−H Bond Sulfenylation and C−N Bond Oxygenation of Enaminones toward the Synthesis of 3‐Sulfenylated Chromones

Abstract

Abstract With 2‐hydroxyphenyl‐functionalized enaminones and thiophenols as the starting materials, the facile synthesis of 3‐sulfenylated chromones has been realized through a KIO 3 ‐catalyzed domino reaction of C−H sulfenylation and subsequent C−N‐cleavage‐based C−O bond formation. The reaction was performed under transition‐metal‐free conditions in ethyl lactate, a bioavailable ecofriendly medium.