Improving test-retest reliability of quantitative electroencephalography using different preprocessing approaches

Abstract

This work aims to assess the effect of preprocessing approaches over test-retest reliability of quantitative electroencephalography measurements. Two electroencephalography sessions were recorded during an eyes-closed resting state condition in 15 young healthy individuals. The second session was 4 to 6 weeks after the first one. Clean recordings were obtained from the implementation of different preprocessing approaches commonly used in the literature. We then estimated the power spectrum density, for each individual and preprocessing approach, in six frequency bands: delta, theta, alpha1, alpha2, beta, and gamma. Test-retest reliability using the intraclass correlation coefficient was calculated for power spectrum in each methodology and frequency band. We found that the test-retest reliability varied considerably across frequency bands and preprocessing approaches. Reliability was higher for theta, alpha1, and alpha2 frequency bands. Also, the use of preprocessing approach that includes a robust reference to average and independent component analysis, can improve test-retest reliability in other bands such as beta and gamma. Results suggest that quantitative electroencephalography are test-retest reliable and can be used in longitudinal studies.