Reward Expectancy Strengthens CA1 Theta and Beta Band Synchronization and Hippocampal-Ventral Striatal Coupling

Abstract

Here we show that temporally discrete cues raising reward expectancy enhance both theta and beta band activity in the hippocampus once goal-directed navigation has been initiated. These rhythmic activities are associated with increased synchronization of neuronal firing patterns in the hippocampus and the connected ventral striatum. When transmitted to downstream target structures, this expectancy-related state of intensified processing in the hippocampus may modulate goal-directed action.