A Randomised, Double-blind, Placebo-controlled Trial of<i>Trichuris suis</i>ova in Active Crohn’s disease

Abstract

Administration of 250-7500 TSO fortnightly over 12 weeks was safe and showed a dose-dependent immunological response, but no TSO dose showed a clinically relevant effect over placebo for induction of clinical remission or response in mildly-to-moderately active, ileocolonic CD.