Chemical Sciences Journal · 2016 · 14 citations · 43 references
EngineeringBioengineeringBiotechnologyBioprocess EngineeringBiosensorsSensorsOptical BiosensingOptical BiosensorsOptical SensorsBioprocess Systems EngineeringExcitationFluorescent BiosensingFluorescent DyesLuminescent BiosensorsOrganic Light-emitting DiodesPhotoluminescenceSensors For Bioprocesses
Micro- and millilitre-scale sensors have become increasingly important in modern biotechnology. Miniaturization and parallelization are also commonly employed in bio-analytical applications, environmental science and bioprocess engineering. This reduction of dimensions to the micro- and milliliter-scale stems from the demand for new sensor systems that enable non-invasive monitoring of bioprocesses in microfluidic or on-chip devices. Highly sensitive optical (bio-) sensors, with operating principles based on photoluminescence intensity or lifetime detection, hold significant promise for meeting the space-limited conditions within miniaturized biotechnological systems. In this context, the properties and applications of OLED-based organic sensors in biotechnology are discussed. The possibleuse of OLEDs as excitation sources in (analytical) biotechnological applications is also examined.
43
All-organic optoelectronic sensor for pulse oximetry
Claire M. Lochner, Yasser Khan, Adrien Pierre et al. · Nature Communications · 2014 · 715 citations · Full text
Separating NADH and NADPH fluorescence in live cells and tissues using FLIM
Thomas S. Blacker, Zoë F. Mann, Jonathan E. Gale et al. · Nature Communications · 2014 · 570 citations · Full text