Biological Activity of Complex Ions Mechanism of Inhibition of Acetylcholinesterase

Abstract

Previous experiments had shown that certain complex ions, whieh are co,ol'dinately saturated metal chelatcR lacking specifie gronps 01' centres, wern for mice aud inhibited acetyleholinestcrasc. As these iOllS nre extremely stable, undergoing no ehange in living organisms, it would be expected that any such effec!' would be physical and not ehcmieal in nature.