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Multi-targeting exploration of new 2-aminothiazolyl quinolones: Synthesis, antimicrobial evaluation, interaction with DNA, combination with topoisomerase IV and penetrability into cells

Medicinal ChemistryMulti-targeting ExplorationBioorganic ChemistryNew 2-Aminothiazolyl QuinolonesTopoisomerase IvMedicineNatural SciencesSynthetic BiologyAntibacterial AgentAntimicrobial ChemotherapyMicrobiologyAntimicrobial CompoundDrug DevelopmentPharmacologyAntimicrobial ResistanceDrug DiscoveryDrug Resistance