Antimicrobial activity of antisense peptide–peptide nucleic acid conjugates against non-typeable<i>Haemophilus influenzae</i>in planktonic and biofilm forms

Abstract

A PNA-peptide that targets acpP, has a 5' membrane-penetrating peptide and has a linker shows excellent activity against planktonic and biofilm NTHi and is associated with a low risk for induction of resistance.