Rosai-Dorfman disease successfully treated with thalidomide

Abstract

Rosai-Dorfman disease, also called sinus histiocytosis with massive lymphadenopathy, is a rare histiocytic condition of unknown etiology first described in 1969.1 Primary cutaneous manifestation without systemic involvement of Rosai-Dorfman disease is even more uncommon.2 Here we present a case of primary cutaneous manifestation of Rosai-Dorfman disease with excellent response to oral thalidomide.