The role of interleukin-1β in pyoderma gangrenosum

Abstract

Pyoderma gangrenosum (PG) is a rare, inflammatory, and necrotizing disease that belongs to the group of neutrophilic dermatosis.1-3 The pathogenesis of PG remains unknown. In the last 2 years, some researchers found a significant increase in interleukin (IL)-1β and in the IL-1β receptor in skin samples of PG patients.