Chelators in Iron and Copper Toxicity

Undetectable Intracellular Free Copper: The Requirement of a Copper Chaperone for Superoxide Dismutase

Tracey Rae, Paul J. Schmidt, Robert A. Pufahl et al. · Science · 1999 · 1.6K citations

Biochemistry, Natural Sciences, Medicine +14

Metal-Protein Attenuation With Iodochlorhydroxyquin (Clioquinol) Targeting Aβ Amyloid Deposition and Toxicity in Alzheimer Disease

Craig Ritchie, Ashley I. Bush, Andrew Mackinnon et al. · Archives of Neurology · 2003 · 974 citations

A sex-linked recessive disorder with retardation of growth, peculiar hair, and focal cerebral and cerebellar degeneration.

John H. Menkes, Milton Alter, Gerd Klaus Steigleder et al. · PubMed · 1962 · 854 citations

Neurological Disorder, Corticobasal Degeneration, Genetics +23

Penicillamine, a new oral therapy for Wilson's disease

J.M. Walshe · The American Journal of Medicine · 1956 · 712 citations

New Oral Therapy, Pharmacology, Experimental Therapeutic +3

Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

Lars Lannfelt, Kaj Blennow, Henrik Zetterberg et al. · The Lancet Neurology · 2008 · 697 citations

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +10