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Bifunctional Thiourea Catalyzed Asymmetric Mannich Reaction Using Trifluoromethyl Aldimine as Trifluoromethyl Building Blocks
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2015
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Asymmetric Mannich ReactionCross-coupling ReactionEngineeringEfficient Bifunctional ThioureaOrganic ChemistryTrifluoromethyl Building BlocksCatalysisTrifluoromethyl AldimineChemistryStereoselective SynthesisAsymmetric CatalysisSynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering
An efficient bifunctional thiourea catalyzed asymmetric Mannich reaction with trifluoromethyl aldimine as trifluoromethyl building block was achieved to give the products in good diastereoselectivity and enantioselectivity.