Palladium–catalyzed Mizoroki–Heck Reaction Using Imidazo[1,5‐ <i>a</i> ]pyridines

Abstract

Abstract We designed a new class of N ‐type ligands bearing an imidazo[1,5‐ a ]pyridine moiety and synthesized seven imidazo[1,5‐ a ]pyridine derivatives. The palladium‐catalyzed Mizoroki–Heck reaction of aryl bromides and chlorides with alkenes using our imidazo[1,5‐ a ]pyridine‐PdCl 2 system afforded the desired products in good‐to‐high yields with the low palladium loadings and short reaction times.