Investigating deformable image registration and scatter correction for CBCT‐based dose calculation in adaptive IMPT

Abstract

For H&N patients, no considerable differences of vCT and CBCT_cor were found. For prostate cases, despite the high dosimetric agreement, the DIR yields incorrect contours, probably due to the more pronounced anatomical changes in the abdomen and the reduced soft-tissue contrast in the CBCT. Using the vCT as prior, these inaccuracies can be overcome and images suitable for accurate delineation and dose calculation in CBCT-based adaptive IMPT can be retrieved from scatter correction of the CBCT projections.