Concepedia

Publication | Open Access

DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer

DOIFull Paper Access

168

Citations

40

References

2016

Year

Nnennaya Kanu, Maria Antonietta Cerone, Gerald Goh, Lykourgos‐Panagiotis Zalmas, Jiřina Bártková, Michelle Dietzen, Nicholas McGranahan, Rebecca F. Rogers, Emily K. Law, Irina Gromova,
Genome biology

Abstract

These data link oncogene, loss of tumour suppressor gene and drug-induced replication stress with APOBEC3B activity, providing new insights into how cytidine deaminase-induced mutagenesis might be activated in tumourigenesis and limited therapeutically.

References

YearCitations

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