Dioxygen-induced oxidative activation of a P–H bond: radical oxyphosphorylation of alkenes and alkynes toward β-oxy phosphonates

Abstract

The dioxygen-induced radical oxyphosphorylation of alkenes and alkynes is presented, wherein a P-H bond was activated by molecular oxygen. Various β-oxy phosphonates could be facilely synthesized without the assistance of any transition metals or extra organic initiators. Mechanistic studies showed that HP(O)Ph₂ acts as a reductant to accelerate oxyphosphorylation.