Publication | Open Access

Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit

Molecular PharmacologyBenzodiazepine Positive ModulatorBiochemistryα5 SubunitMedicineFunctional SelectivityBehavioral PharmacologyMechanism Of ActionPharmacological AgentNeuropharmacologyPharmacotherapyPharmacologyGabaa ReceptorsInhibitory NeurotransmittersDrug Discovery