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PAPP-A, IGFBP-4 and IGF-II are secreted by human adipose tissue cultures in a depot-specific manner

DOIFull Paper Access

30

Citations

30

References

2016

Year

Mette Faurholdt Gude, Rikke Hjortebjerg, Claus Oxvig, Anne Anker Thyø, Nils E. Magnusson, Mette Bjerre, Steen B. Pedersen, Jan Frystyk
European Journal of Endocrinology

Abstract

Human adipose tissue cultures secrete enzymatically active PAPP-A, IGFBP-4 and IGF-II in a depot-specific manner, suggesting differential regulation of IGF activity. Further, IGF-II appears to be more prominent than IGF-I. Finally, VAT appears more GH responsive than SAT.

References

YearCitations

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