Concepedia

Publication | Open Access

Association of <i>GBA</i> Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease

DOIFull Paper Access

221

Citations

31

References

2016

Year

Marie Y. Davis, Catherine O. Johnson, James B. Leverenz, Daniel Weintraub, John Q. Trojanowski, Alice Chen‐Plotkin, Vivianna M. Van Deerlin, Joseph F. Quinn, Kathryn A. Chung, Amie L. Peterson‐Hiller,
JAMA Neurology

Abstract

GBA variants predict a more rapid progression of cognitive dysfunction and motor symptoms in patients with PD, with a greater effect on PIGD than tremor. Thus, GBA variants influence the heterogeneity in symptom progression observed in PD.

References

YearCitations

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