Integration of HPLC-based fingerprint and quantitative analyses for differentiating botanical species and geographical growing origins of <i>Rhizoma coptidis</i>

Abstract

It is necessary to use the three R. coptidis species differentially in TCM clinical practice. Daodi C. chinensis medicinal materials have better quality than most non-Daodi ones, and so they should be preferred for TCM prescription. The combination of HPLC-based fingerprint analysis and quantification of multi-ingredients with statistical analysis provided an effective approach for species discrimination and quality evaluation of R. coptidis.