Increased Intestinal Microbial Diversity Following Fecal Microbiota Transplant for Active Crohnʼs Disease

Abstract

In this open-label study, FMT led to an expansion in microbial bacterial diversity in patients with active CD. FMT was overall safe, although the clinical response was variable. Determining donor microbial factors that influence clinical response is needed before randomized clinical trials of FMT in CD.