Synthesis of 1-azulenyl ketones by Brønsted acid mediated hydration of 1-azulenylalkynes

Abstract

Preparation of 1-azulenyl ketones was achieved by metal-free hydration of 1-azulenylalkynes with trifluoroacetic acid in good to excellent yields. In the cases of the reaction of alkyne <bold>1m</bold>, isocoumarin congener <bold>4</bold> was obtained in excellent yield.