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A novel, sensitive and selective method of UPLC/MS–MS for rapid simultaneous determination of midodrine and its active metabolite desglymidodrine in human plasma: Application to support bioequivalence study in healthy human volunteers

BiochemistryHealthy Human VolunteersBioanalysisMass SpectrometryPharmacologyMetabolomic ProfilingHuman PlasmaAnalytical ChemistryActive Metabolite DesglymidodrineMetabolic ProfilingMedicineHuman MetabolismPharmacokineticsChromatographyDrug Analysis