Publication | Open Access
Mechanism of action of pimavanserin in Parkinson’s disease psychosis: targeting serotonin 5HT2A and 5HT2C receptors
222
Citations
40
References
2016
Year
NeurotransmitterPsychopharmacologySerotonin 5Ht2aPharmacotherapySocial SciencesMolecular PharmacologyMedicinal ChemistryDisease PsychosisNovel AgentParkinson ’NeurochemistryPsychoactive DrugPsychiatryNeuropharmacologyDopaminePharmacologyNeuroscienceBiological PsychiatryMedicineDrug Discovery
Pimavanserin, a novel agent approved for the treatment of Parkinson's disease psychosis, has potent actions as an antagonist/inverse agonist at serotonin 5HT2A receptors and less potent antagonist/inverse agonist actions at 5HT2C receptors.
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