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Simultaneous Near‐Infrared and Two‐Photon In Vivo Imaging of H<sub>2</sub>O<sub>2</sub> Using a Ratiometric Fluorescent Probe based on the Unique Oxidative Rearrangement of Oxonium

215

Citations

27

References

2016

Year

Abstract

A new ratiometric fluorescent H<sub>2</sub> O<sub>2</sub> probe, benzopyrylium-coumarin (BC), is designed by using an oxonium moiety as the unique H<sub>2</sub> O<sub>2</sub> response site. The BC probe exhibits an extremely large emission shift of 221 nm in response to H<sub>2</sub> O<sub>2</sub> , and is successfully applied for the simultaneous near-infrared and two-photon imaging of H<sub>2</sub> O<sub>2</sub> in living cells, mouse-liver tissues, and zebrafish.

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