Antidepressant-like effects of long-term sarcosine treatment in rats with or without chronic unpredictable stress

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

Social Sciences, Behavioral Sciences, Psychology +9

A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression

Carlos A. Zarate, Jaskaran Singh, Paul J. Carlson et al. · Archives of General Psychiatry · 2006 · 3.8K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

Nanxin Li, Boyoung Lee, Rongjian Liu et al. · Science · 2010 · 2.9K citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors

Sungho Maeng, Carlos A. Zarate, Jing Du et al. · Biological Psychiatry · 2007 · 1.1K citations

Medicine, Neuroscience, Pharmacology +16

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

Nanxin Li, Rong-Jian Liu, Jason M. Dwyer et al. · Biological Psychiatry · 2011 · 1.1K citations

Medicine, Neuroscience, Pharmacology +17