Cooperative Dynamics of AR and ER Activity in Breast Cancer

Abstract

This study suggests that AR plays a previously unrecognized role in supporting E2-mediated ER activity in ER⁺/AR⁺ breast cancer cells, and that enzalutamide may be an effective therapeutic in ER⁺/AR⁺ breast cancers. Mol Cancer Res; 14(11); 1054-67. ©2016 AACR.