Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

Peter Peciar, Maroš Eckert, Roman Fekete, Viliam Hrnčiar

Strojnícky časopis/Journal of Mechanical Engineering · 2016 · 15 citations · 28 references

DOIFull text

Open access

Concepts

Abstract

Abstract This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel, Kawakita, Cooper-Eaton and Adams compaction equations. Experimental material was determined by measuring its parameters as particle size distribution, angle of wall friction and flow properties and for more detailed characteristics of the material particles, microscopy images of the powder before and after compressing were created.

References

28