Non-Enzymatic Glucose Biosensor Based on CuO-Decorated CeO2 Nanoparticles

Abstract

Copper oxide (CuO)-decorated cerium oxide (CeO₂) nanoparticles were synthesized and used to detect glucose non-enzymatically. The morphological characteristics and structure of the nanoparticles were characterized through transmission electron microscopy, X-ray photoelectron spectroscopy, and X-ray diffraction. The sensor responses of electrodes to glucose were investigated via an electrochemical method. The CuO/CeO₂ nanocomposite exhibited a reasonably good sensitivity of 2.77 μA mM^-1cm^-2, an estimated detection limit of 10 μA, and a good anti-interference ability. The sensor was also fairly stable under ambient conditions.