Ruthenium-catalyzed Decarboxylative and Dehydrogenative Formation of Highly Substituted Pyridines from Alkene-tethered Isoxazol-5(4<i>H</i>)-ones

Kazuhiro Okamoto, Kohei Sasakura, Takuya Shimbayashi, Kouichi Ohe

Chemistry Letters · 2016 · 22 citations · 40 references

Concepts

Abstract

Abstract A ruthenium-catalyzed reaction of alkene-tethered isoxazol-5(4H)-ones affording pyridines has been developed. Di-, tri-, and tetrasubstituted pyridines were obtained from various isoxazolones in good yields.

References

40