Concepedia

Publication | Open Access

Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo

DOIFull Paper Access

47

Citations

35

References

2016

Year

Natalie Porat‐Shliom, Amber Jean Tietgens, Christina M. Van Itallie, Lynn Vitale‐Cross, Michal Jarník, Olivia J. Harding, James M. Anderson, J. Silvio Gutkind, Roberto Weigert, Irwin M. Arias
Hepatology

Abstract

LKB1 plays a critical role in regulating the maintenance of TJ and paracellular permeability, which may explain how various drugs, chemicals, and metabolic states that inhibit the LKB1/AMPK pathway result in cholestasis. (Hepatology 2016;64:1317-1329).

References

YearCitations

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