Blood pressure estimation from photoplethysmogram using latent parameters

Abstract

Non-invasive cuff-less Blood Pressure (BP) estimation from Photoplethysmogram (PPG) is a well known challenge in the field of affordable healthcare. This paper presents a set of improvements over an existing method that estimates BP using 2-element Windkessel model from PPG signal. A noisy PPG corpus is collected using fingertip pulse oximeter, from two different locations in India. Exhaustive pre-processing techniques, such as filtering, baseline and topline correction are performed on the noisy PPG signals, followed by the selection of consistent cycles. Subsequently, the most relevant PPG features and demographic features are selected through Maximal Information Coefficient (MIC) score for learning the latent parameters controlling BP. Experimental results reveal that overall error in estimating BP lies within 10% of a commercially available digital BP monitoring device. Also, use of alternative latent parameters that incorporate the variation in cardiac output, shows a better trend following for abnormally low and high BP.