Toxicity of dual HER2-blockade with pertuzumab added to anthracycline versus non-anthracycline containing chemotherapy as neoadjuvant treatment in HER2-positive breast cancer: The TRAIN-2 study - Concepedia

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Toxicity of dual HER2-blockade with pertuzumab added to anthracycline versus non-anthracycline containing chemotherapy as neoadjuvant treatment in HER2-positive breast cancer: The TRAIN-2 study

DOI Full Paper Access

38

Citations

22

References

2016

Year

Mette S. van Ramshorst, Erik van Werkhoven, Aafke H. Honkoop, Vincent O. Dezentjé, Irma M. Oving, Ingrid A.M. Mandjes, Inge Kemper, Carolien H. Smorenburg, Jacqueline M. Stouthard, Sabine C. Linn,

Abstract

Pertuzumab in combination with FEC-T mostly causes neutropenia, and when added to PTC mostly causes diarrhea. Significant cardiac toxicity is rare with both regimens, and toxicity is overall well manageable.

References

	Year	Citations

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