Synthesis and insecticidal activity of novel pyrimidine derivatives containing urea pharmacophore against <i>Aedes aegypti</i>

Abstract

A practical synthetic route for pyrimidine derivatives is presented. This study suggests that these pyrimidine derivatives exhibit some activity against the yellow fever mosquito and, with further structure modification, could be novel lead compounds for the development of insecticides against mosquitoes. © 2016 Society of Chemical Industry.