RSC Advances · 2016 · 47 citations · 49 references
MedicineBiochemistryMedicinal ChemistryAntimicrobial PharmacologyBacteriologyDrug DiscoveryAntibacterial AgentsAntibacterial PharmacologyAntibacterial Drug DevelopmentBactericidal AgentsBacteriostatic AgentsBromine ChemistryNovel Antibacterial Drug Discovery
The unusual di-bromo product, <bold>5b</bold>, confirmed by spectral analysis, showed the most potency with the lowest IC<sub>50</sub> and MIC values, with excellent activity comparable to the standard antibacterial drug, tetracycline.
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