Concepedia

Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome

Nesa Marti, José A. Galván, Amit V. Pandey, Mafalda Trippel, Coya Tapia, Michel Müller, Aurel Perren, Christa E. Flück

Molecular and Cellular Endocrinology · 2016 · 74 citations · 22 references

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22

Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome

Fertility and Sterility · 2004 · 9.1K citations

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Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1‒AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

T.M. Penning, Michael E. Burczynski, Joseph M. Jez et al. · Biochemical Journal · 2000 · 572 citations · Full text

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The Biochemical Basis for Increased Testosterone Production in Theca Cells Propagated from Patients with Polycystic Ovary Syndrome

Velen L. Nelson, Kenan Qin, Robert L. Rosenfield et al. · The Journal of Clinical Endocrinology & Metabolism · 2001 · 393 citations

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Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1–AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

T.M. Penning, Michael E. Burczynski, Joseph M. Jez et al. · Biochemical Journal · 2000 · 350 citations

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Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer

Kai‐Hsiung Chang, Rui Li, Mahboubeh Papari-Zareei et al. · Proceedings of the National Academy of Sciences · 2011 · 338 citations

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