Combining genomewide association study and lung <scp>eQTL</scp> analysis provides evidence for novel genes associated with asthma

Abstract

Combining GWAS with subsequent lung eQTL analysis revealed disease-associated SNPs regulating lung mRNA expression levels of potential new asthma genes. Adding BHR to the asthma definition does not lead to an overall larger genetic effect size than analysing (doctor's diagnosed) asthma.