Concepedia

Tumor-Specific Binding of Radiolabeled PEGylated GIRLRG Peptide: A Novel Agent for Targeting Cancers

Vaishali Kapoor, David Dadey, Kim Phi Phụng Nguyễn, Scott A. Wildman, Kelly Hoye, Arpine Khudanyan, Nilantha Bandara, Buck E. Rogers, Dinesh Thotala, Dennis E. Hallahan

Journal of Nuclear Medicine · 2016 · 26 citations · 25 references

DOIFull text

Open access

Abstract

GIRLRG peptide specifically binds to the ATPase domain of GRP78. Radiolabeled PEG-GIRLRG could be used to target various cancers. Further studies would be required to translate PEG-GIRLRG peptide into the clinic.

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