Visible-Light Photoredox Catalyzed Three-Component Cyclization of 2<i>H</i>-Azirines, Alkynyl Bromides, and Molecular Oxygen to Oxazole Skeleton

Lili Chen, Hongji Li, Pinhua Li, Lei Wang

Organic Letters · 2016 · 78 citations · 43 references

Concepts

Abstract

A novel three-component cyclization of 2H-azirines, alkynyl bromides, and molecular oxygen under visible-light photoredox catalysis at room temperature has been developed, which provides a direct approach to a wide range of substituted oxazoles in moderate to good yields.

References

43