Enkephalin-Fentanyl Multifunctional Opioids as Potential Neuroprotectants for Ischemic Stroke Treatment

Mohammad Rashedul Islam, Li Yang, Yeon Sun Lee, Victor J. Hruby, Vardan T. Karamyan, Thomas J. Abbruscato

Current Pharmaceutical Design · 2016 · 28 citations · 0 references

Abstract

In summary, the results of this study suggest that the multifunctional fluorinated enkephalin analog, LYS739 can be considered as a potential lead for ischemic stroke research and may provide advantages given the multimeric peptide-opiate structure.