Amitraz and its metabolite differentially activate <i>α</i>‐ and <i>β</i>‐adrenergic‐like octopamine receptors

Abstract

Although both amitraz and DPMF acted as OAR agonists, the metabolite DPMF was more potent than amitraz and differentially activated α- and β-AL OARs. The present findings provide a basis for studies to examine the mechanism of amitraz resistance and to develop novel acaricides and insecticides. © 2016 Society of Chemical Industry.