Effects of the Ultra–High-Frequency Electrical Field Radiofrequency Device on Mouse Skin: A Histologic and Molecular Study

Abstract

These results suggest that the device may facilitate replacement of subcutaneous fat tissue with new collagen in association with the increased mRNA levels in TGF-β and vascular endothelial growth factor. Therefore, this device may effectively reduce adipose tissue and achieve facial contouring in addition to skin tightening.