Synthesis of some biologically active pyrazoles and C-nucleosides

Abstract

(5,6-Dihydronaphtho[1',2':4,5]thieno[2,3-d]pyrimidin-11-yl)-hydrazine (1) was used as a precursor for preparation of some novel 1-(5,6-dihydronaphtho[1',2':4,5]thieno[2,3-d]pyrimidin-11-yl)-pyrazole derivatives 2-7. Also,some acyclic and cyclic C-nucleosides 8 and 10-12 were prepared by treating compound 1 with aldoses. Some of the prepared products showed potent antimicrobial activity.