Hippocampal lipid differences in Alzheimer's disease: a human brain study using matrix‐assisted laser desorption/ionization‐imaging mass spectrometry

Abstract

Matrix-assisted laser desorption/ionization-imaging mass spectrometry and our analysis workflow provide a novel method to investigate specific lipid changes in hippocampal subfields. Future work will focus on elucidating the role that specific lipid differences in each subfield play in AD pathogenesis.