Asperterpenes A and B, two unprecedented meroterpenoids from Aspergillus terreus with BACE1 inhibitory activities

Changxing Qi, Jian Bao, Jianping Wang, Hucheng Zhu, Yongbo Xue, Xiaochuan Wang, Hua Li, Weiguang Sun, Weixi Gao, Yongji Lai,

Chemical Science · 2016 · 96 citations · 28 references

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Abstract

Asperterpenes A and B, two BACE1 inhibitors with unprecedented carbon skeletons isolated from<italic>Aspergillus terreus</italic>, exhibit potent anti-Alzheimer's disease activity.

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