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Immune-mediated hemolytic anemia in a horse
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1991
Year
ImmunologyPathologyEducationImmunotherapyAplastic AnemiaHematologyImmunohaematologyChemotherapeutic DrugsLaboratory MedicineAnimal PhysiologyVeterinary PhysiologyEquine-assisted TherapyAutoimmune DiseaseImmune-mediated Hemolytic AnemiaAutoimmunityAnimal ScienceVeterinary ScienceRbc SpherocytosisMedicineBlood Transfusion
An 18-year-old Quarter Horse gelding was determined to have immune-mediated hemolytic anemia after detection of autoagglutination of RBC spherocytosis as well as a positive direct Coombs test result. A lack of response to treatment with corticosteroids necessiated the administration of cyclophosphamide and azathioprine. The anemia resolved after treatment with chemotherapeutic drugs.