Diencephalic placement of estradiol and sexual receptivity in the female rat

Abstract

Behavioral receptivity, as indicated by the presence of the lordosis reflex, could be elicited from spayed rats after implantation of estradiol in the medial-basal preoptic and anterior hypothalamic regions. Hormone implants elsewhere in the hypothalamus or blank tubing implants throughout the hypothalamus did not produce this effect. Subcutaneous implants were equally ineffective for producing behavioral receptivity.